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Real members of MyPsoriasisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Anyone On Otezla?

Anyone On Otezla?

posted March 8
A MyPsoriasisTeam Member

Otezla did not help me. Getting back on my Enbrel today. it's the only thing that has helped me.

posted March 8
A MyPsoriasisTeam Member

Didn't even make it through the first week on Otezla .... total loss of appetite, dry heaves, sudden and devastating depression. I'm usually pretty tough, but Otezla kicked me badly. Thank god it was free, and not the $3600/month they wanted to charge me for it!

posted April 2
A MyPsoriasisTeam Member

I have been on Otezla since August of last year and it took 3 months for me to start to feel it working (Im also on Cosentyx).

Eat before taking the Otezla this will prevent upset stomach and the bathroom issues can’t assist you on that because I did not suffer with that issue and I did not develop any depression but I did not have issues with depression prior to Otezla either.

posted March 8
A MyPsoriasisTeam Member

Otezla was rough for me for 6-8 weeks with headaches, nausea and diarrhea. Eventually figured out eating before taking makes a world of difference, and severity of GI symptoms decreased by week 6. I am almost a year in now and am so glad I toughed it out as I rarely have GI symptoms now and all of my PsA symptoms are kept to a more manageable level - quality of life much improved.

posted May 31
A MyPsoriasisTeam Member

Have had similiar reactions. Have vomited twice and know it's the Otezla. Have not thrown up for over 13 years so know it's this drug. I cut back to one pill a day and still had reaction. Now taking one dose every other day with food. It's better, but I consider this a poison for my body and am attempting to find more natural treatment.

posted April 4

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