Stay away from Methotrexate and Neotigarson. If prescribed ask the doctor/dermatologist about the side effects. Both can affect the liver and kidneys, especially Neo. You notice the kidney pain after about a month. You are not supposed to drink alcohol while taking MTX. I was never told this when prescribed. Needless to say neither MTX or Neo have worked for me.

Would also be interested in answers to this as I'm about to start PUVA with methetrexate.

cheers i have bloods every month for the last 6 years and all come back great i had a scan and found fibrosis now they have also found erratic heart rate and artheritise i will be finding out if it is safe to continue with methetrexate this month my head says no get off it xx and cheers for the good luck i need all i can get i am sick of being told its cos of the methetrexate xxx ahhh