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Real members of MyPsoriasisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has Anyone Had Experience With METHOTREXATE As A Treatment? Did It Work For You? How Well Did It Work Or Not Work? Any Complications?

Has Anyone Had Experience With METHOTREXATE As A Treatment? Did It Work For You? How Well Did It Work Or Not Work? Any Complications?

I start this oral medication tomorrow with a steroid cream. I have done plenty of research on the pill, but I dont have anyone I know who has had this one. Just want to make sure I know all sides, good or bad, it all helps.

posted July 21, 2016
A MyPsoriasisTeam Member

It has only been a month but it has been up and down. They decreased the dose because it was making me tired, nauseaous, mind fog, I couldn't stay awake and when I was I couldn't focus on anything. Then horrible stomach pains. Went to my rheumatologist, come to find out they didn't do all the blood tests they needed to start the medication and my white blood cell count the was way over normal and liver enzymes were low. He suggested folic acid on the days that I am not taking the methotrexate to prevent some of the side effects and to run more blood tests to see why the numbers are messed up. Not sure if this one is going to stick unfortunately. However my skin is smoother...not clearing up but smooth less itch and no flakes, so that's a plus.

posted August 7, 2016
A MyPsoriasisTeam Member

Hi @A MyPsoriasisTeam Member if they are going to start you on similar drugs i would recommend boosting up your immune system as much as you can (particulary during winter!) Ive had this arthritis for over 2 years now and ive had to listen to my body a lot..eg rest when feeling fatigued or run down and just take things easy. I find i dont have as much energy as i used to but i suppose i exercised 5 days a week before the arthritis struck. If you have any questions let me know!

posted July 25, 2016
A MyPsoriasisTeam Member

Brilliant drug. It affected my liver unfortunately as nd i had to stop.

posted August 6
A MyPsoriasisTeam Member

Oh, why not... I started methotrexate 5 weeks ago, again. I was put on injections because last time and every time I took pills I got stomach issues. Surprisingly it is working well right now but I definitely need a biologic to help with everything. My doctor said it will really help the biological when I start it. I have had no issues with it this time around. I have been on this 5 different times over the past ten years.

posted May 20
A MyPsoriasisTeam Member

I was going to answer when I saw this was asked 6 yrs ago.

posted May 20

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