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Has Anyone Had Experience With METHOTREXATE As A Treatment? Did It Work For You? How Well Did It Work Or Not Work? Any Complications?

Has Anyone Had Experience With METHOTREXATE As A Treatment? Did It Work For You? How Well Did It Work Or Not Work? Any Complications?

I start this oral medication tomorrow with a steroid cream. I have done plenty of research on the pill, but I dont have anyone I know who has had this one. Just want to make sure I know all sides, good or bad, it all helps.

A MyPsoriasisTeam Member said:

It has only been a month but it has been up and down. They decreased the dose because it was making me tired, nauseaous, mind fog, I couldn't stay awake and when I was I couldn't focus on anything. Then horrible stomach pains. Went to my rheumatologist, come to find out they didn't do all the blood tests they needed to start the medication and my white blood cell count the was way over normal and liver enzymes were low. He suggested folic acid on the days that I am not taking the methotrexate to prevent some of the side effects and to run more blood tests to see why the numbers are messed up. Not sure if this one is going to stick unfortunately. However my skin is smoother...not clearing up but smooth less itch and no flakes, so that's a plus.

posted almost 6 years ago
A MyPsoriasisTeam Member said:

Hi @A MyPsoriasisTeam Member if they are going to start you on similar drugs i would recommend boosting up your immune system as much as you can (particulary during winter!) Ive had this arthritis for over 2 years now and ive had to listen to my body a lot..eg rest when feeling fatigued or run down and just take things easy. I find i dont have as much energy as i used to but i suppose i exercised 5 days a week before the arthritis struck. If you have any questions let me know!

posted almost 6 years ago
A MyPsoriasisTeam Member said:

Oh, why not... I started methotrexate 5 weeks ago, again. I was put on injections because last time and every time I took pills I got stomach issues. Surprisingly it is working well right now but I definitely need a biologic to help with everything. My doctor said it will really help the biological when I start it. I have had no issues with it this time around. I have been on this 5 different times over the past ten years.

posted about 1 month ago
A MyPsoriasisTeam Member said:

I was going to answer when I saw this was asked 6 yrs ago.

posted about 1 month ago
A MyPsoriasisTeam Member said:

I have had really bad stomach aches from methatrexate....six, 5 mg pills once a week. Didn't have the issue with four pills, but that next step up....wow, I didn't experience the nausea commonly reported, but just really afull stomach aches that would last from between three to eight days. 9the severity of the pain would vary throughout each day,, often getting much worse mid-day. Sleeping with unrelenting stomach pain was a bummer.Felt, as someone else said like being kicked in tthe stomach by an elephant. I split the dose up, taking them throughout the day. I tried two at a time spaced three times for the day. I did one pill every second hour. I've gotten on a biologic so am being tapered down, and it is now minimally bothersome, but the six tablet dose was an overload to my digestive system.

posted about 2 months ago
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