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Real members of MyPsoriasisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Methotrexate Or Acitretin?

Methotrexate Or Acitretin?

I'm literally covered in psoriasis. I had a appointment today in the dermatology department. I was given 2 options to go on acitretin or methotrexate. I was told to have a think about all weekend and to call on Mondaywith a decision. so the docs can have it prescribed to me. has anyone being on either of them. which one is better? Imy 24 and I do like to go out out and have
drinks.

posted September 2, 2016
A MyPsoriasisTeam Member

I tried methotrexate but couldn't tolerate it very well but I've heard a lot of people say it's worked for them. I'm also covered in psoriasis have been for 5+ years am currently having the light therapy treatment and using a new thing called enstillar which is a foam that you spray on and it's really cold and then you rub it in and it's amazing I've been using it for a week and can see a difference. I'd highly recommend asking your doctor to try you with enstillar X

posted September 2, 2016
A MyPsoriasisTeam Member

MTX worked a bit but I ended up on both MTX and remicade (infliximab)
That's rather a big decision you have to make at your young age.
MTX and acetretin are very damaging to a foetus therefore you cannot get pregnant while on it or for a year after. However if you need them take them and see.
MTX is probably the best choice. It has less sideffects .

posted September 11, 2016
A MyPsoriasisTeam Member

edit to the above, it never worked for me.

posted September 7, 2016
A MyPsoriasisTeam Member

i was prescribed methatrexate and had to sign waivers in case something went wrong. I asked about side effects and Dr. Duke in Ottawa said it will make your skin go thin. I thought he meant for the 10 weeks I was on it, not for the rest of my life. This drug changes the way your body makes skin, for the past 20 years every time I bump into a branch or a cat paw I bleed way too easily and way too much.

posted September 7, 2016
A MyPsoriasisTeam Member

I was on methotrexate and it worked for about 10 years but then psoriasis came back and liver count changed so I had to stop taking methotrexate, sorry

posted September 7, 2016

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