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Real members of MyPsoriasisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyPsoriasisTeam Member asked a question 💭
Farmington, NY

Diagnosed with osteoporosis and psoriatic arthritis and psoriasis I have been on Taltz for the last 7 years

June 23, 2025
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MyPsoriasisTeam

Leflunomide (not Luflinamide) is generally considered safe when used appropriately, but there are important safety considerations to discuss with your doctor. The medication works by calming the immune system to reduce inflammation and protect joints from damage.

Common side effects can include
- Joint tenderness
- Pain
- Show Full Answer

Leflunomide (not Luflinamide) is generally considered safe when used appropriately, but there are important safety considerations to discuss with your doctor. The medication works by calming the immune system to reduce inflammation and protect joints from damage.

Common side effects can include:
- Joint tenderness
- Pain
- Fatigue
- Skin reactions Important safety concerns to discuss with your doctor:
- Regular liver function monitoring may be needed
- Should be avoided during pregnancy due to potential birth defects
- May not be suitable if you have kidney disease, severe liver disease, or other conditions affecting blood/bone marrow
- Interactions with alcohol and certain medications including acetaminophen
- May need to adjust or avoid if planning pregnancy

Work closely with your healthcare provider to determine if leflunomide is appropriate given your specific health situation and current medications.

June 23, 2025

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