Yes it could be a number of factors. People could be prone to things genetically and not know it yet even. I have a former co-worker who's still a friend of mine she got multiple myeloma but she said she's not surprised because both her parents died from cancers. She didn't say it was the same kind but still there's a genetic link. Taking something may or may not pose a risk it depends on what serious side effects are for that medication. Thankfully many people have tried the medications and became the case studies that way. That should be listed and disclosed up front. Newer medications scare me because there's not enough research done for people to be aware of what the serious side effects could end up being.

I hope for the sake of all taking medication that everyone stays safe and those that are not able to avoid greater risks heal quickly from that.

Back in the day when I didn't research my medicine because I didn't have access to and it wasn't shared with me by doctors maybe they didn't know fully?, I took my risks. Thinking I had to treat what was the problem and the doctor should know better what to do. Now I thoroughly research what I can upfront. Kind of knowledge is power but yet James I do agree Google is a search engine but it is limited as to its ability. It even says that some points if you look further down it may be prone to inaccuracy. To me it kind of became the replacement for the encyclopedia Britannica. Just don't know how much it follows the outline of that though. Back then they had to have people research stuff to put that in the Britannica. Now I don't know if it's just all AI generated. That's where the error comes in to play possibly in that.

Interesting point, @A MyPsoriasisTeam Member. I thought the same thing when I read Peter's question so I asked the all knowing Google.
There is a confounding variable here-our autoimmune disease itself which increases our risk of cancer.
Is it the methotrexate or the PsA/Ps? Since those of us with PsA or Ps are more likely to be on methotrexate than the general population you could say it was the methotrexate but it might just be our disease leading to the increased risk. Truth is, we are exposed to so many carcinogens, I think it is rare to know with any statistically significant certainty what specific agent causes any cancer (aside from exposure to things like asbestos).
I guess the point is Peter can't takemethotrexate anymore.
For my rheumatologist, he said methotrexate is a last resort; only when biologics and other options fail would he go with methotrexate.

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A MyPsori...

Yes. It was diagnosed as being caused by the methotrexate.

Well that's really not the typical course it takes. Are you sure it wasn't something else that caused that? I'm just asking because it is well known that methotrexate is a well-established chemotherapy medication used to treat various cancers by destroying fast-dividing cells.

Sometimes when we have other conditions or any kind of family history of cancers we could be prone to getting something. We just never know until it develops.

That would be one of the biggest ironies that it's used as an anti-cancer medication to end up causing a cancer. I've never heard of that before. And I think that drug has been around for quite some time now.

I know it can affect other parts of the body like white blood cell count and it can affect the liver. That's why these have to be monitored all the time if on it.