It sounds like Skyrizi may not be working as well as it once did for your psoriasis, and now you're dealing with joint pain in your fingers and toes too. That's a lot to manage, and it makes complete sense to be asking these questions.
Skyrizi is actually FDA-approved for both plaque psoriasis and psoriatic arthritis Show Full Answer
It sounds like Skyrizi may not be working as well as it once did for your psoriasis, and now you're dealing with joint pain in your fingers and toes too. That's a lot to manage, and it makes complete sense to be asking these questions.
Skyrizi is actually FDA-approved for both plaque psoriasis and psoriatic arthritis (PsA). It works by targeting a protein called IL-23 that drives inflammation. In clinical trials, more than half of PsA patients saw improvements in joint swelling and inflammation after 24 weeks.
However, not every medication works the same for everyone. If Skyrizi isn't controlling your symptoms well enough anymore, there are other options worth discussing with your doctor, including:
- Other biologics that target different parts of the immune system
- DMARDs like methotrexate, which can help both skin and joint symptoms
- Oral medications like JAK, PDE4, or TYK2 inhibitors Regarding Zepbound specifically — that falls outside the scope of psoriasis treatment, so it's best to keep that conversation with your doctor separate from your psoriasis management plan.
The most important next step is talking to both your dermatologist and a rheumatologist about your joint symptoms. A rheumatologist specializes in PsA and can help find a treatment that addresses both your skin and joint concerns together.
June 11
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