MyPsoriasisTeam

Skyrizi (risankizumab-rzaa) is a biologic medication that many people with moderate to severe plaque psoriasis have found effective. Clinical studies show that 3 in 4 people saw a 90% improvement in skin symptoms by week 16, with 84–88% achieving "clear or almost clear skin."

Members of MyPsoriasisTeam have highlighted Show Full Answer

Skyrizi (risankizumab-rzaa) is a biologic medication that many people with moderate to severe plaque psoriasis have found effective. Clinical studies show that 3 in 4 people saw a 90% improvement in skin symptoms by week 16, with 84–88% achieving "clear or almost clear skin."

Members of MyPsoriasisTeam have highlighted some key benefits:

- Convenient dosing — only four injections per year after initial doses
- Effective skin clearance, even when other treatments have failed
- Can also help with joint symptoms (psoriatic arthritis)

That said, some considerations to keep in mind:

- Results can take time — patience through the first few months is important
- Insurance approval can be challenging, and costs can be high without financial assistance
- There is an increased risk of infection As for side effects, most are manageable but worth knowing about. The most common ones include:

- Upper respiratory infections (affecting about 13% of people in trials)
- Headache
- Fatigue
- Injection site reactions
- Fungal infections

There are also some rare but serious side effects to watch for:

- Severe allergic reactions (like anaphylaxis)
- Serious infections, including tuberculosis (TB testing is required before starting)
- Liver issues

Always keep your doctor informed of any new or worsening symptoms. Before starting Skyrizi, your doctor will review your health history, check for TB, and make sure your vaccinations are up to date. Live vaccines should not be given while on Skyrizi.

If cost is a concern, AbbVie offers support programs that may help eligible people pay as little as $0 per dose — worth asking your healthcare provider about!

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

Treatments

Skyrizi