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Bimzelx (bimekizumab-bkzx) is a biologic medication approved by the U.S. Food and Drug Administration (FDA) for treating moderate to severe psoriasis in adults who qualify for systemic therapy (which works throughout the whole body) or phototherapy.
These insights are based on 131 comments about Bimzelx from MyPsoriasisTeam members. These are the experiences of a small number of members and are not meant to be medical advice.
Bimzelx is a biologic medication that works by targeting and blocking certain proteins called interleukin (IL)-17A and IL-17F and a combination protein called interleukin 17-AF. These proteins play key roles in the inflammation that drives psoriasis symptoms like raised patches and scaling.
Doctors prescribe Bimzelx for adults whose psoriasis significantly impacts their quality of life and hasn’t responded well to other treatments. It’s typically considered when topical treatments haven’t been effective enough or when psoriasis covers large areas of the body.
The medication is given as subcutaneous injections (shots under the skin) using prefilled syringes or autoinjectors. After proper training from a healthcare provider, you can give the injections yourself at home, rotating between injection sites like the thigh, abdomen, or upper arm.
These insights are based on 131 comments about Bimzelx from MyPsoriasisTeam members.Many members reported that their skin improved quickly after starting Bimzelx. While some felt joint pain relief, others said their joint pain did not improve. Several members said getting insurance coverage for the medicine was difficult, but the manufacturer’s financial assistance program was helpful in reducing costs.
Connect with others who understand life with psoriasis. Join MyPsoriasisTeam for free.
These are the most common side effects from clinical trials of Bimzelx:
These occurred in between 1 percent and 15 percent of people taking Bimzelx.
Serious but rare side effects that require immediate medical attention include:
UCB, the drug’s manufacturer, offers the Bimzelx Navigate program with nurse support and financial assistance options. People with private insurance may pay as little as $5 per dose through the savings card program.
For those experiencing insurance delays, the Bimzelx Navigate Bridge program provides temporary access for $15 per dose. Visit the website at the link above or call 833-931-6877 for more information.
Before starting Bimzelx, your doctor will order a tuberculosis test and liver function tests. You should be up to date on all vaccinations, as live vaccines aren’t recommended during treatment.
Tell your doctor about all medications and supplements you take, as well as any medical conditions you have — especially any history of infections, liver problems, or inflammatory bowel disease. Discuss any history of depression or mood disorders.
Bimzelx is also FDA-approved for psoriatic arthritis, nonradiographic axial spondyloarthritis, ankylosing spondylitis, and hidradenitis suppurativa.
If you miss a dose, take it as soon as possible and resume your regular schedule. If you are pregnant or thinking of becoming pregnant, talk to your doctor. There is a pregnancy registry for people exposed to Bimzelx.
These answers are fact-checked by our editorial staff.
How effective is Bimzelx for clearing psoriasis symptoms?
In clinical trials, 84 percent to 93 percent of people achieved clear or almost clear skin by week 16, with 59 percent to 68 percent achieving complete skin clearance.
What specific tests are required before starting Bimzelx treatment?
Tuberculosis testing, liver enzyme tests, alkaline phosphatase, and bilirubin tests are required. All age-appropriate vaccinations should also be completed.
Can Bimzelx cause mood changes or depression?
Bimzelx may increase the risk of suicidal thoughts or behavior. Monitor for new or worsening mood changes, and contact your doctor right away if these occur.
What should I do if I forget to take my Bimzelx dose?
Take the missed dose as soon as you remember, then continue with your regular dosing schedule.
On MyPsoriasisTeam, people share their experiences with psoriasis, get advice, and find support from others who understand.
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