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About MyPsoriasisTeam

Orencia is a prescription medication approved by the Food and Drug Administration (FDA) to treat active psoriatic arthritis in adults. Orencia may be referred to by its drug name, Abatacept.

Orencia is an immunomodulator, or in other words, a drug that modulates the immune system. It is also considered a biologic. It is a fusion protein created by genetic engineering. Orencia is believed to work by modifying the immune system. Specifically, Orencia binds to antigen presenting cells (APCs) and prevents them from signaling T cells to attack the connective tissues.

How do I take it?
Orencia is administered as a subcutaneous injection once a week or intravenous infusion once every four weeks.

Orencia is available as single-use, prefilled syringe or autoinjector for subcutaneous injection.

Side effects
The FDA-approved label for Orencia lists common side effects including headache, nausea, and cold or flu symptoms.

Rare but serious side effects listed for Orencia can include hypersensitivity reactions and increased risk for infections, including severe infections.

For answers to frequently asked questions about exposure to Orencia during pregnancy and breastfeeding, visit the experts at

For more details about this treatment, visit:

Orencia – Bristol-Myers Squibb

Orencia (Abatacept) for Psoriasis Questions

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