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List of Treatments for Psoriasis

See what members are saying about treatments for psoriasis and psoriatic arthritis, the side effects to expect, and the drug basics.

All treatment information is medically reviewed · September 22, 2026

Cyltezo (Adalimumab-Adbm) for Psoriasis and Psoriatic Arthritis

Cyltezo (adalimumab-adbm) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis and active psoriatic arthritis.

Avsola (Infliximab-Axxq) for Psoriasis

Avsola (infliximab-axxq) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with chronic severe plaque psoriasis.

Yuflyma (Adalimumab-Aaty) for Psoriasis and Psoriatic Arthritis

Yuflyma (adalimumab-aaty) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis or active psoriatic arthritis.

Yusimry (Adalimumab-Aqvh) for Psoriasis and Psoriatic Arthritis

Yusimry (adalimumab-aqvh) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis and active psoriatic arthritis.

Starjemza (Ustekinumab-Hmny) for Psoriasis

Starjemza (ustekinumab-hmny) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 and older with moderate to severe plaque psoriasis.

Idacio (Adalimumab-Aacf) for Psoriasis and Psoriatic Arthritis

Idacio (adalimumab-aacf) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis and active psoriatic arthritis.

Wezlana (Ustekinumab-Auub) for Psoriasis

Wezlana (ustekinumab-auub) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat moderate to severe plaque psoriasis in adults and children ages 6 years and older.

Eticovo (Etanercept-Ykro) for Psoriasis

Eticovo (etanercept-ykro) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children 4 years and older with moderate to severe plaque psoriasis or psoriatic arthritis.

Icotyde (Icotrokinra) for Psoriasis

Icotyde (icotrokinra) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 12 and older with moderate to severe plaque psoriasis.

Calcitrene (Calcipotriene)

Overview
Calcitrene is approved by the U.S. Food and Drug Administration (FDA) for the treatment of plaque psoriasis in adults. It is prescribed for individuals with mild to moderate plaque psoriasis and should not be…

Zoryve (Roflumilast) for Plaque Psoriasis

Zoryve (roflumilast) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat plaque psoriasis in certain adults and children. It comes as a cream and a topical foam.

Steqeyma (Ustekinumab-Stba) for Psoriasis

Steqeyma (ustekinumab-stba) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 years and older with moderate to severe plaque psoriasis.

Yesintek (Ustekinumab-Kfce) for Psoriasis

Yesintek (ustekinumab-kfce) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 years and older with moderate to severe plaque psoriasis.

Selarsdi (Ustekinumab-Aekn) for Psoriasis

Selarsdi (ustekinumab-aekn) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 and older with moderate to severe plaque psoriasis.

Spevigo (Spesolimab-Sbzo) for Generalized Pustular Psoriasis

Spevigo (spesolimab-sbzo) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat generalized pustular psoriasis (GPP) in adults and children ages 12 and older who weigh at least 40 kilograms.

Imuldosa (Ustekinumab-Srlf) for Psoriasis

Imuldosa (ustekinumab-srlf) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 and older with moderate to severe plaque psoriasis.

Otulfi (Ustekinumab-Aauz) for Psoriasis

Otulfi (ustekinumab-aauz) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 and older with moderate to severe plaque psoriasis.

Pyzchiva (Ustekinumab-Ttwe) for Psoriasis

Pyzchiva (ustekinumab-ttwe) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 and older with moderate to severe plaque psoriasis.

Simlandi (Adalimumab-Ryvk) for Psoriasis and Psoriatic Arthritis

Simlandi (adalimumab-ryvk) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis and active psoriatic arthritis.

Bimzelx (Bimekizumab-Bkzx)

Bimzelx (bimekizumab-bkzx) is a biologic medication approved by the U.S. Food and Drug Administration (FDA) for treating moderate to severe psoriasis in adults who qualify for systemic therapy (which works throughout the whole body) or phototherapy.

Vtama (Tapinarof Cream) for Psoriasis

Vtama (tapinarof cream) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with plaque psoriasis.

Sotyktu (Deucravacitinib) for Psoriasis

Sotyktu (deucravacitinib) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe plaque psoriasis.

Rinvoq (Upadacitinib) for Psoriatic Arthritis

Rinvoq (upadacitinib) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 2 and older with active psoriatic arthritis.

Sorilux (Calcipotriene) for Psoriasis

Sorilux (calcipotriene) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat plaque psoriasis of the scalp and body in adults and children ages 4 and older.

Hadlima (Adalimumab-Bwwd) for Psoriasis and Psoriatic Arthritis

Hadlima (adalimumab-bwwd) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis and active psoriatic arthritis.

Hulio (Adalimumab-Fkjp) for Psoriasis and Psoriatic Arthritis

Hulio (adalimumab-fkjp) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis or active psoriatic arthritis.

Hyrimoz (Adalimumab-Adaz) for Psoriasis and Psoriatic Arthritis

Hyrimoz (adalimumab-adaz) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis and active psoriatic arthritis.

Ixifi (Infliximab-Qbtx) for Psoriasis

Ixifi (infliximab-qbtx) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with chronic severe plaque psoriasis.

The drug maintains its official FDA approval. However, its manufacturer, Pfizer, chose not to bring it to the U.S. market because they already distribute a different, competing infliximab biosimilar called Inflectra.

Pfizer had developed Ixifi independently before acquiring the company that made Inflectra, leaving them with two identical types of products. They decided to keep Inflectra for the U.S. market.

Wynzora (Calcipotriene and Betamethasone Dipropionate) for Psoriasis

Wynzora (calcipotriene and betamethasone dipropionate) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat plaque psoriasis in adults ages 18 and older.

Abrilada (Adalimumab-Afzb) for Psoriasis

Abrilada (adalimumab-afzb) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis.

Skyrizi (Risankizumab-Rzaa) for Psoriasis

Skyrizi (risankizumab-rzaa) is a biologic medication approved by the U.S. Food and Drug Administration (FDA) for adults with moderate to severe psoriasis who need systemic (bodywide) therapy or phototherapy.

Duobrii (Halobetasol Propionate/Tazarotene) for Plaque Psoriasis

Duobrii (halobetasol propionate and tazarotene) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with plaque psoriasis.

Xeljanz (Tofacitinib) for Psoriatic Arthritis

Xeljanz (tofacitinib) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating adults and children ages 2 years and older with active psoriatic arthritis.

Ilumya (Tildrakizumab-asmn) for Psoriasis

Ilumya (tildrakizumab-asmn) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe plaque psoriasis.

Simponi Aria (Golimumab) for Psoriatic Arthritis

Simponi Aria (golimumab) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat active psoriatic arthritis in people 2 years of age and older.

Orencia (Abatacept) for Psoriatic Arthritis

Orencia (abatacept) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat people ages 2 and older with active psoriatic arthritis.

Rasuvo (Methotrexate) for Psoriasis

Rasuvo (methotrexate) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to control symptoms of severe, hard-to-treat, disabling psoriasis in adults who have not responded well enough to other treatments.

Renflexis (Infliximab-Abda) for Psoriasis

Renflexis (infliximab-abda) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with chronic severe plaque psoriasis.

Tremfya (Guselkumab) for Psoriasis

Tremfya (guselkumab) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating moderate to severe plaque psoriasis in adults who may benefit from injections, pills, or light therapy.

Siliq (Brodalumab)

Overview
Siliq is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat moderate to severe psoriasis in adults. Siliq may be prescribed in cases where systemic therapy and phototherapy are…

Inflectra (Infliximab-Dyyb) for Psoriasis

Inflectra (infliximab-dyyb) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with chronic severe plaque psoriasis.

Erelzi (Etanercept-Szzs) for Psoriasis

Erelzi (etanercept-szzs) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 4 and older with chronic moderate to severe plaque psoriasis. Note that Erelzi is not currently commercially available in the U.S.

Amjevita (Adalimumab-Atto) for Psoriasis

Amjevita (adalimumab-atto) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis.

Acthar Gel (Repository Corticotropin Injection) for Psoriatic Arthritis

Acthar Gel (repository corticotropin injection) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for short-term use with other treatment during a flare of psoriatic arthritis in adults.

Taltz (Ixekizumab) for Psoriasis

Taltz (ixekizumab) is a biologic medication approved by the U.S. Food and Drug Administration (FDA) for treating moderate to severe plaque psoriasis in adults and children 6 years and older who may benefit from systemic therapy or light therapy.

Cimzia (Certolizumab Pegol) for Psoriasis

Cimzia (certolizumab pegol) is a biologic medication approved by the U.S. Food and Drug Administration (FDA) for treating moderate to severe plaque psoriasis in adults who are candidates for systemic therapy (treatment that works throughout the whole body) or phototherapy (a treatment that uses ultraviolet light to improve psoriasis symptoms).

Otezla (Apremilast)

Otezla (apremilast) is an oral medication called a phosphodiesterase 4 (PDE4) inhibitor, approved by the U.S. Food and Drug Administration (FDA) for treating psoriasis and psoriatic arthritis in adults and children ages 6 and older.

Remicade (Infliximab) for Psoriasis

Remicade (infliximab) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with chronic severe plaque psoriasis.

Simponi (Golimumab) for Psoriatic Arthritis

Simponi (golimumab) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with active psoriatic arthritis.

Soriatane (Acitretin) for Psoriasis

Soriatane (acitretin) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with severe psoriasis.

Stelara (Ustekinumab) for Psoriasis

Stelara (ustekinumab) is a medication approved by the U.S. Food and Drug Administration (FDA) for treating moderate to severe plaque psoriasis in adults and children 6 years and older who may benefit from injections, pills, or light therapy.

Neoral (Cyclosporine)

Overview
Neoral is a prescription medication originally approved by the U.S. Food and Drug Administration (FDA) in 1983. Neoral is approved to treat severe psoriasis in adults who do not respond to other treatments…

Taclonex (Calcipotriene/Betamethasone Dipropionate) for Plaque Psoriasis

Taclonex (calcipotriene/betamethasone dipropionate) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat plaque psoriasis in people ages 12 years and older.

Humira (Adalimumab)

Humira (adalimumab) is a biologic medication approved by the U.S. Food and Drug Administration (FDA) for treating moderate to severe psoriasis in adults.

Tazorac (Tazarotene) for Psoriasis

Tazorac (tazarotene) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat people with plaque psoriasis.

Trexall (Methotrexate) for Psoriasis

Trexall (methotrexate) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with severe psoriasis.

Enbrel (Etanercept) for Psoriasis

Enbrel (etanercept) is a biologic medication approved by the U.S. Food and Drug Administration (FDA) for treating moderate to severe psoriasis in adults and children 4 years and older.

Dovonex (Calcipotriene) for Plaque Psoriasis

Dovonex (calcipotriene) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat plaque psoriasis.

Cosentyx (Secukinumab) for Psoriasis

Cosentyx (secukinumab) is a biologic medicine approved by the U.S. Food and Drug Administration (FDA) to treat moderate to severe plaque psoriasis in people age 6 and older who need full-body treatment or light therapy.

Vectical (Calcitriol)

Overview
Vectical is a prescription medication approved by the U.S. Food and Drug Administration (FDA) in 2009. Vectical is used to treat mild to moderate plaque psoriasis in adults 18 years and older. Vectical is also…

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