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Taclonex is a prescription drug approved by the Food and Drug Administration (FDA) to treat psoriasis vulgaris in people age 18 and older. Taclonex can be used to treat psoriasis on the scalp and nails in people ages 12 and up.

Taclonex is a combination drug containing both Betamethasone and Calcipotriene. Betamethasone is a high-potency glucocorticoid steroid, a drug that suppresses the immune system. Calcipotriene is a synthetic form of vitamin D. Taclonex is believed to work by reducing inflammation and slowing the growth of cells.

How do I take it?
Taclonex is applied topically to the affected areas once a day.

Side effects
The two drugs that comprise Taclonex can cause various side effects.

Side effects of Calcipotriene may include irritation, burning, redness, flaking, dry skin, itching, and worsening of psoriasis. Rarely, Calcipotriene may result in skin atrophy, hyperpigmentation (darkening of the skin), hypercalcemia, swollen blood vessels in the affected area, and folliculitis (infected or inflamed hair follicles).

Common side effects of Betamethasone include irritation, burning, redness, and dry skin. These effects are likely to fade as your body becomes accustomed to the medication.

The risk for serious side effects of Betamethasone or other topical corticosteroids increase with the potency of the drug, prolonged use, use over larger areas of skin, and adding bandages or other covering (occlusion) after applying the medication. Like systematic corticosteroids, serious side effects may include weight gain, mood or vision changes, fatigue, puffy face, trouble sleeping, and, in children, slowed growth.

For answers to frequently asked questions about exposure to topical corticosteroids during pregnancy and breastfeeding, visit the experts at

Taclonex (Betamethasone/Calcipotriene) for Psoriasis Questions

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