Connect with others who understand.

sign up log in
About MyPsoriasisTeam
PSORIASIS
NEWS

Biologic Treatment for Psoriasis May Reduce Psoriatic Arthritis Risks

Posted on October 13, 2021
See how 163 members reacted on this article
Medically reviewed by
Ariel D. Teitel, M.D., M.B.A.
Article written by
Emily Wagner, M.S.

  • A new study has found that treating psoriasis with biologics may reduce the risk for developing psoriatic arthritis.
  • The study followed 1,719 participants who were treated with topicals, conventional disease-modifying antirheumatic drugs (DMARDs), or biologic DMARDs for several years.
  • The researchers concluded that biologic DMARDs may lower the risk of developing psoriatic arthritis compared to the other treatments, but more studies are needed.

A new study has found that treating a person’s psoriasis with biologics can lower their chances of developing psoriatic arthritis compared to other treatments. Compared to topicals, conventional DMARDs may also be more effective in reducing a person’s risk of psoriatic arthritis, according to the findings.

Researchers from the Hospital Italiano de Buenos Aires in Buenos Aires, Argentina looked at the effects of using disease-modifying antirheumatic drugs for treating and preventing psoriasis and psoriatic arthritis.

Psoriasis is an inflammatory skin disease that causes dry patches and scales known as plaques to form on the skin. The disease affects more than 7.5 million adults in the United States alone. Psoriatic arthritis results from an abnormal immune response that causes inflammation in a person’s joints as well as an overproduction of skin cells.

There are several treatments for psoriasis, including topical treatments, light therapy, and biologics. Biologics are human-made proteins that help dampen the immune system in inflammatory diseases. These drugs also help slow the progression of the disease.

DMARDs can be classified in two groups, conventional DMARDs and biologic DMARDs. Conventional DMARDs are chemotherapy drugs, such as methotrexate and leflunomide. Biologic DMARDs block specific mediators of inflammation, such as tumor necrosis factor (TNF) alpha, interleukin 17 (IL-17), and IL-12/23.

The researchers were interested in studying the effects of biologics, along with other psoriasis treatments, to see if they prevent psoriatic arthritis. The study followed 1,719 participants, 1,387 (81 percent) of whom were treated with topicals, 229 (13 percent) with conventional DMARDS, and 103 (6 percent) with biologic DMARDs. Researchers followed up with participants at a median time of 7.3 years after the study began to determine which ones had developed psoriatic arthritis.

At the follow-up, researchers found that a total of 239 participants developed psoriatic arthritis. Of them, 231 had been using topicals, whereas only six participants had used conventional DMARDs and two had used biologic DMARDs. The study also found that people who developed psoriatic arthritis had their psoriasis earlier than others, had a higher body mass index (BMI), and were more often male.

With these results, the authors concluded that biologic DMARDs may be more effective for preventing psoriatic arthritis than other kinds of psoriasis treatments. However, more research is necessary, as the authors noted that other studies had found conflicting results.

Ariel D. Teitel, M.D., M.B.A. is the clinical associate professor of medicine at the NYU Langone Medical Center in New York. Review provided by VeriMed Healthcare Network. Learn more about him here.
Emily Wagner, M.S. holds a Master of Science in biomedical sciences with a focus in pharmacology. She is passionate about immunology, cancer biology, and molecular biology. Learn more about her here.

A MyPsoriasisTeam Member said:

Shame :-( - here in AU mine is subsided by govt Medicare system so lucky d

posted 4 days ago

hug

Recent news

(IFPA)The 17th annual World Psoriasis Day will be celebrated internationally on Friday, Oct....
Posted 10/14/2021

Global Psoriasis Community Unites for World Psoriasis Day on October 29

(IFPA)The 17th annual World Psoriasis Day will be celebrated internationally on Friday, Oct....
Posted 10/14/2021
Topical steroids were the first and longest treatment I have used for my psoriasis. When first...
Posted 10/12/2021

My Perspective: My Love-Hate Relationship With Topical Steroids for Psoriasis

Topical steroids were the first and longest treatment I have used for my psoriasis. When first...
Posted 10/12/2021
Researchers looked over data from thousands of people who underwent testing for suspected...
Posted 10/07/2021

Psoriasis and Psoriatic Arthritis Are Linked With Heart Disease

Researchers looked over data from thousands of people who underwent testing for suspected...
Posted 10/07/2021
A childhood diagnosis of psoriasis or eczema can be stressful and affect the quality of life of...
Posted 10/06/2021

Parental Mindfulness Improves Quality of Life for Children With Psoriasis

A childhood diagnosis of psoriasis or eczema can be stressful and affect the quality of life of...
Posted 10/06/2021
When I was diagnosed with psoriasis, I received a narrow and potentially incomplete picture of...
Posted 10/05/2021

My Perspective: The Stress of Searching for a Root Cause of Psoriasis

When I was diagnosed with psoriasis, I received a narrow and potentially incomplete picture of...
Posted 10/05/2021
Figuring out how to dress comfortably with psoriasis has been a journey. When I first experienced...
Posted 09/30/2021

My Perspective: Dressing for My Psoriasis

Figuring out how to dress comfortably with psoriasis has been a journey. When I first experienced...
Posted 09/30/2021
The International Psoriasis Council (IPC) recently proposed a new classification system for...
Posted 09/29/2021

IPC’s New Psoriasis Classification Could Expand Treatment Access

The International Psoriasis Council (IPC) recently proposed a new classification system for...
Posted 09/29/2021
A new study examined the relationship between psoriasis symptoms, alcohol misuse, and obesity in...
Posted 09/28/2021

Alcohol Misuse and Obesity May Inhibit Some Psoriasis Treatments

A new study examined the relationship between psoriasis symptoms, alcohol misuse, and obesity in...
Posted 09/28/2021
The Centers for Disease Control and Prevention (CDC) recommended Pfizer COVID-19 vaccine booster...
Posted 09/24/2021

COVID-19 Boosters and Additional Doses for People With Psoriasis: Current Guidelines

The Centers for Disease Control and Prevention (CDC) recommended Pfizer COVID-19 vaccine booster...
Posted 09/24/2021
In a recently published study, researchers examined the effects of exercise on heart health in...
Posted 09/22/2021

Physical Activity Supports Heart Health for People With Psoriasis

In a recently published study, researchers examined the effects of exercise on heart health in...
Posted 09/22/2021
psoriasis News

Become a Subscriber

Get the latest news about psoriasis sent to your inbox.

Not now, thanks

Privacy policy
psoriasis News

Thank you for signing up.

close