Lynn, I'm on 12.5 mg methotrexate every Monday, 1mg folic acid daily, and now 400mg Celebrex daily. I start Enbrel in a few weeks once it's cleared with insurance. It's only been 2 weeks but honestly the side effects haven't been that terrible and my plaques seem to be getting a little better. I'm hopeful that after a few more weeks or months of treatment my skin will be clear and my pain will be better or hopefully gone.

I dont know if Cosenyx is working yet but I too want SOMETHING to help. The fatigue and depression kick in also and make it even more difficult. At least I'm not the only person with reactions to meds. I will say my rheumatologist has been working close with me. I will keep updated on the outcome.

I have tried Enbrel, Humira, Stelara and now will start Cosenyx next week. It has been a long road.

I started on Sulfasalazine in February - I'm very tired and the pain has worsened. They warned me that bodily fluids may become yellow! I don't have any sense at all that it's making any difference. So I can't really add to your experience Angela, but I really hope you notice an improvement with the new meds.

That's good to know since I just switched to Celebrex! What's your dosage? He wrote mine for 400mg once daily....with the meloxicam I'd have to take it twice a day to get any effect and therefore I'd run out before my refill was due...hope that doesn't happen with the Celebrex.