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Real members of MyPsoriasisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyPsoriasisTeam Member asked a question 💭
Leesburg, FL
April 19, 2025
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A MyPsoriasisTeam Member

Personally, this has been my biggest issue. I've tried many, many different biologics and DMARDS to address the PsA, joint pain, swelling etc. I've only had a few that ever did anything to help the Psoriasis. The biggest heartbreak, is I've had NONE of any of these treatments ever help me with the PsA, joint pain, swelling etc. Not one!!! I'm now on IVIG therapy and Cellcept. I'm not really seeing much in the way of results, but these are 2 different forms of treatment you could explore further.

April 27, 2025
MyPsoriasisTeam

For non-biologic treatment options, disease-modifying antirheumatic drugs (DMARDs) like methotrexate and sulfasalazine can help manage joint pain and swelling. These medications work by suppressing parts of the immune response that cause inflammation.

Nonsteroidal anti-inflammatory drugs (NSAIDs), both over-the-counter and Show Full Answer

For non-biologic treatment options, disease-modifying antirheumatic drugs (DMARDs) like methotrexate and sulfasalazine can help manage joint pain and swelling. These medications work by suppressing parts of the immune response that cause inflammation.

Nonsteroidal anti-inflammatory drugs (NSAIDs), both over-the-counter and prescription strength, are often used as a first-line treatment to reduce pain and inflammation. Common options include ibuprofen and naproxen. Other medication options include:

- Apremilast (Otezla), a PDE4 inhibitor that helps reduce inflammation
- Corticosteroid injections directly into affected joints for quick relief
- JAK inhibitors like tofacitinib (Xeljanz) and upadacitinib (Rinvoq), typically used when other treatments haven't worked well

Remember that finding the right medication may take time, and your doctor will help determine the best treatment plan based on your specific symptoms and condition severity.

April 19, 2025
A MyPsoriasisTeam Member

Has anyone had any experience with cimzia or remicade?

April 27, 2025

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