Personally, this has been my biggest issue. I've tried many, many different biologics and DMARDS to address the PsA, joint pain, swelling etc. I've only had a few that ever did anything to help the Psoriasis. The biggest heartbreak, is I've had NONE of any of these treatments ever help me with the PsA, joint pain, swelling etc. Not one!!! I'm now on IVIG therapy and Cellcept. I'm not really seeing much in the way of results, but these are 2 different forms of treatment you could explore further.
April 27, 2025
For non-biologic treatment options, disease-modifying antirheumatic drugs (DMARDs) like methotrexate and sulfasalazine can help manage joint pain and swelling. These medications work by suppressing parts of the immune response that cause inflammation.
Nonsteroidal anti-inflammatory drugs (NSAIDs), both over-the-counter and Show Full Answer
For non-biologic treatment options, disease-modifying antirheumatic drugs (DMARDs) like methotrexate and sulfasalazine can help manage joint pain and swelling. These medications work by suppressing parts of the immune response that cause inflammation.
Nonsteroidal anti-inflammatory drugs (NSAIDs), both over-the-counter and prescription strength, are often used as a first-line treatment to reduce pain and inflammation. Common options include ibuprofen and naproxen. Other medication options include:
- Apremilast (Otezla), a PDE4 inhibitor that helps reduce inflammation
- Corticosteroid injections directly into affected joints for quick relief
- JAK inhibitors like tofacitinib (Xeljanz) and upadacitinib (Rinvoq), typically used when other treatments haven't worked well
Remember that finding the right medication may take time, and your doctor will help determine the best treatment plan based on your specific symptoms and condition severity.
April 19, 2025