Does Otezla become less effective over time?
Yes, like other psoriatic arthritis medications, Otezla (apremilast) can become less effective over time for some people. This happens when your body develops antibodies that recognize the medication as a foreign substance and work to neutralize it.
A MyPsoriasisTeam member Show Full Answer
Does Otezla become less effective over time?
Yes, like other psoriatic arthritis medications, Otezla (apremilast) can become less effective over time for some people. This happens when your body develops antibodies that recognize the medication as a foreign substance and work to neutralize it.
A MyPsoriasisTeam member shared their experience trying Otezla before moving to biologics. They found that while taking the medication, it completely upset their gastrointestinal system and didn't make a dent in their psoriasis symptoms.
Signs your medication may be losing effectiveness:
* You're not getting the same level of symptom relief as before
* The medication seems to work initially but doesn't last as long between doses
* You feel fine for part of the dosing period but symptoms return before your next dose
If you notice Otezla becoming less effective, talk with your doctor about adjusting your treatment plan. Some side effects may improve over time, while loss of effectiveness often requires switching to a different medication. Your doctor can help determine whether what you're experiencing is temporary or if it's time to explore other options.
February 12
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