What's the connection between psoriatic arthritis and diabetes, and what are the risk factors?
People with psoriatic arthritis face a significantly higher risk of developing type 2 diabetes compared to the general population. While diabetes affects 2.4-14.8% of people overall, the rate can reach up to 20.2% in those with Show Full Answer
What's the connection between psoriatic arthritis and diabetes, and what are the risk factors?
People with psoriatic arthritis face a significantly higher risk of developing type 2 diabetes compared to the general population. While diabetes affects 2.4-14.8% of people overall, the rate can reach up to 20.2% in those with psoriatic arthritis.
Several key factors explain this connection:
Chronic Inflammation
The inflammation driving psoriatic arthritis also promotes insulin resistance. Elevated levels of inflammatory proteins like TNF-alpha can impair how insulin receptors work, making it harder for your body to manage blood sugar levels.
Physical Inactivity
Joint pain and stiffness can make staying active challenging. Reduced physical activity contributes to weight management issues, which increases diabetes risk.
Obesity
Many people with psoriatic arthritis have higher body mass indexes. Research shows insulin resistance is more common in those with severe psoriatic arthritis, higher BMI, and psoriasis that developed later in life.
Genetic Factors
Some research suggests shared genes may make people more susceptible to both conditions.
Certain Treatments
Long-term use of systemic corticosteroids can worsen insulin resistance. However, some treatments may have neutral or even protective effects on blood sugar control.
Managing both conditions involves avoiding inflammatory trigger foods, maintaining healthy weight, staying active within your abilities, and working closely with your healthcare team to monitor blood sugar levels.
March 2
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