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A MyPsoriasisTeam Member asked a question 💭
Pittsburgh, PA
April 11
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What causes ankle pain and leg neuropathy in psoriatic arthritis?

Ankle pain in psoriatic arthritis typically results from inflammation in the joints. When PsA affects your ankles, the immune system attacks healthy tissue, causing swelling, stiffness, and discomfort.

Leg neuropathy (nerve damage) can occur with PsA Show Full Answer

What causes ankle pain and leg neuropathy in psoriatic arthritis?

Ankle pain in psoriatic arthritis typically results from inflammation in the joints. When PsA affects your ankles, the immune system attacks healthy tissue, causing swelling, stiffness, and discomfort.

Leg neuropathy (nerve damage) can occur with PsA, though it may not always be directly caused by the condition itself. Research shows that people with PsA may experience neuropathy due to:

* Oversensitive nerves that send pain signals when they shouldn't
* More severe PsA symptoms like swollen joints
* Other health conditions common in people with PsA, such as diabetes, vitamin deficiencies, thyroid problems, or kidney disease
* Certain medications

Neuropathy in the legs typically causes numbness, tingling, burning sensations, or weakness that can make walking and daily activities more challenging. Treatment options for ankle pain and leg neuropathy

For ankle pain, treatments focus on controlling inflammation:

* NSAIDs (like ibuprofen) to reduce pain and swelling
* DMARDs to slow disease progression
* Biologics or JAK inhibitors to target immune system inflammation
* Steroid injections directly into the ankle joint for quick relief
* Physical therapy to maintain mobility and strengthen muscles

For leg neuropathy, several approaches can help:

* Antidepressants like duloxetine or nortriptyline
* Anti-seizure medications like gabapentin or pregabalin
* Topical creams containing lidocaine
* Pain medications including NSAIDs
* TENS (transcutaneous electrical nerve stimulation) therapy
* Physical therapy to improve strength and movement

Keeping your PsA well-controlled with DMARDs, biologics, or JAK inhibitors can help reduce both ankle pain and neuropathy symptoms. Regular check-ups with your rheumatologist are important to find the right treatment combination for you.

April 11

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