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Vitamin D for Psoriasis: Benefits and Uses

Posted on February 23, 2021
Medically reviewed by
Diane M. Horowitz, M.D.
Article written by
Bethany J. Sanstrum, Ph.D.

Increasing your vitamin D intake can be a valuable step toward controlling your psoriasis symptoms. The nutrient can be obtained naturally from certain foods and from sunlight exposure, as well as from oral supplements and creams. Vitamin D is best known for its role in calcium absorption, which is vital for bone and teeth health. However, it’s also important for supporting the health of other systems — notably, the immune system and skin.

If you have psoriasis, you know that it’s caused by an overactive immune response that leads to inflammation and itchy skin buildup. Treatments for psoriasis work by targeting the immune system’s response or by helping to relieve symptoms.

How Can Vitamin D Benefit People With Psoriasis?

Vitamin D — which is often made in a layer of the skin called the epidermis — plays an important role in skin health. Research shows that people with psoriasis tend to have lower levels of vitamin D. Low levels of the nutrient can increase skin-cell proliferation, which can contribute to psoriasis lesions. On the other hand, high doses of vitamin D have been shown to reduce skin-cell proliferation and inflammation.

Vitamin D treatments may be taken orally or applied directly to the skin.

Topical Vitamin D

Topical vitamin D has been used to treat psoriasis since the 1980s. Several clinical studies have found topical vitamin D can help psoriatic skin lesions as effectively as corticosteroids.

Many MyPsoriasisTeam members have reported that applying vitamin D benefits their skin. “Topical vitamin D helps keep my flaking down and is inexpensive!” wrote one member.

“Try liquid vitamin D at 5,000 units,” a second member recommended. “It goes on a little greasy, but your skin sucks it up really quick. In about 10 minutes ... it's all gone, and a little goes a long way.”

A benefit of topical treatments is that the vitamin D targets the skin lesions, so any potential side effects are usually limited to the skin.

Oral Vitamin D

The benefits of taking oral vitamin D supplements are less clear. Large research studies have measured the severity and intensity of psoriasis in people who took oral vitamin D supplements. Although some participants showed improvement after six months, the researchers did not find a significant improvement overall. Another clinical study showed that oral vitamin D increased vitamin D levels in the blood and reduced psoriasis severity compared to a placebo group.

Given the mixed evidence, it’s best to follow your doctor’s recommendations. Some MyPsoriasisTeam members report benefiting from taking vitamin D tablets. “My internist has told me to increase my vitamin D3 to 10,000 milligrams. (I was on 2,000 milligrams and had increased it to 5,000 milligrams),” one member shared. “My blood work shows that it is working and helping. For some people, it can be helpful under a doctor’s care.”

What Are Sources of Vitamin D?

There are several sources you can turn to for increasing your vitamin D intake. Talk to your doctor about the options that may be best for your specific diagnosis.

Ultraviolet (UV) Light

When bare skin is exposed to sunlight, the body makes vitamin D. Outdoor sun exposure can be an important source of vitamin D for the body. However, sun exposure can also increase the risk of skin cancer, so sunscreen is recommended — even though it reduces the body’s production of vitamin D.

Phototherapy offers an alternative source of UV light. UV light comes in two forms: UVA and UVB. Research has found that vitamin D production is maximized with UVB exposure that is given at low doses that do not burn the skin. Health care offices offer phototherapy equipment that specifically produces UVB light for treating skin and increasing vitamin D production, with minimized cancer risk.

Topical Treatments

Vitamin D analogues are drugs designed to act very similarly to natural vitamin D. The vitamin D analogue Dovonex (calcipotriene) has been in use since the early 1990s and is shown to reduce the psoriasis symptoms. It may be applied to the affected skin alone or in combination with topical corticosteroids. Other vitamin D treatments are also available for topical use.

Oral Supplements

Oral vitamin D comes in two forms: vitamins D2 and D3. Vitamin D2 is less potent than vitamin D3, but both can efficiently increase vitamin D levels. Vitamin D3 is available as an over-the-counter supplement. However, you should use it under the guidance of a health care provider, because it can interact with other medications and cause side effects.

Food

Food is the safest source of vitamin D, according to the National Psoriasis Foundation. Some foods naturally contain vitamin D, while others are fortified with it, meaning extra vitamin D is added to them. Fatty fish — such as cod, salmon, trout, mackerel, and tuna — have some of the highest levels of natural vitamin D. Cheese and egg yolks can provide a small fraction of the daily recommended amount. Foods that are often fortified with vitamin D include milk, plant-based milks, orange juice, yogurt, and cereals. Including these foods in your diet can help to maintain a healthy level of vitamin D.

Are There Side Effects of Vitamin D?

Getting too much vitamin D can have negative side effects. You’re unlikely to get an unsafe amount of the nutrient from food or sunlight. However, you could get too much from supplemental sources.

High levels of vitamin D can cause damage to your kidneys, blood vessels, and heart. In extreme cases, they can cause death. More often, excess vitamin D can lead to high levels of calcium in the blood due to increased calcium absorption. High calcium can cause side effects such as nausea, vomiting, dehydration, confusion, weakness, and kidney stones.

For safety, consult with your health care provider before taking over-the-counter vitamin D supplements. They may check your vitamin D levels, via blood work, prior to recommending a supplement.

Find Your Team

MyPsoriasisTeam is a community of over 88,000 people living with psoriasis. Members come together to ask questions, give advice, and share their stories with others who understand life with psoriasis.

Have you used vitamin D to manage your psoriasis symptoms? What tips do you have to share? Leave a comment below or start a conversation on MyPsoriasisTeam.

All updates must be accompanied by text or a picture.
Diane M. Horowitz, M.D. is an internal medicine and rheumatology specialist. Review provided by VeriMed Healthcare Network. Learn more about her here.
Bethany J. Sanstrum, Ph.D. holds a doctorate in cell and molecular biology with a specialization in neuroscience from the University of Hawaii at Manoa. Learn more about her here.

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