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Real members of MyPsoriasisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Humira Losing Effectiveness

Humira Losing Effectiveness

I have been on Humira for about 8 months. At the start it worked well, but for the past 2 months I have had flare ups. Has anyone else had the problem of a biologic that has stopped working? If so, what do you think caused it?
I'm seeing my Derm this week. I hope I can get some answers.

posted January 15, 2018
A MyPsoriasisTeam Member

Some Humira patients actually form antibodies against the drug. Your rheumatologist can run a humira antibody blood test to see if that is why you are no longer responding to it.

posted July 13, 2021
A MyPsoriasisTeam Member

You just have to try them all to find the one that works for your body, I tried Enbrel, Humira, Remicade infusions and Stelara, but only Taltz has worked for six years for me!!

posted July 18
A MyPsoriasisTeam Member

I am currently on cosentyx. It's two injections once a month. I have been on it for about three months and I'm about 95% clear. I had a bad flare up about a week ago on me.scalp and ears that was very painful. It started to clear up after about four days. I've been taking different medications for over 30 years and cosentyx is the only one that has worked so far.

posted November 26, 2018
A MyPsoriasisTeam Member

Unfortunately that is a common occurrence. They tend to stop working after a while. Sometimes years and sometimes months... So you just have to keep trying until you find another that works...

posted June 10, 2019
A MyPsoriasisTeam Member

ask your dermatologist about tremfya its a new drug injectable . Im still on my 29 week clinical trial things seem to be going very well. google to see if there are any clinical trials in your area its really been good for me plus u get paid too

posted June 25, 2018

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FDA’s Approval of Cyltezo, a Biosimilar to Humira, May Mean Lower Psoriasis Treatment Costs

FDA’s Approval of Cyltezo, a Biosimilar to Humira, May Mean Lower Psoriasis Treatment Costs

A MyPsoriasisTeam Member

I don't think you are telling the whole story. And are oversimplifying things
As someone who uses biologics, I don't want to be injecting my body with a biosimilar, similar being the key word… read more

posted May 27

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