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Real members of MyPsoriasisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyPsoriasisTeam Member asked a question 💭
Antioch, TN
July 2, 2025
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A MyPsoriasisTeam Member

Doctor gave me folic acid for nausea.

July 3, 2025
A MyPsoriasisTeam Member

Yeah it may have helped but I still was ill for days( folic )

July 5, 2025
A MyPsoriasisTeam Member

Yes. I’ve tried it several times. Both the pill and the injections. The injection of methotrexate was a little better for me but it still made me ill

July 2, 2025
MyPsoriasisTeam

Yes, nausea is one of the most common side effects of methotrexate. While the timing can vary between individuals, many MyPsoriasisTeam members report experiencing nausea and other gastrointestinal issues after taking their dose.

There's a helpful tip that might reduce these symptoms - you can try splitting your weekly Show Full Answer

Yes, nausea is one of the most common side effects of methotrexate. While the timing can vary between individuals, many MyPsoriasisTeam members report experiencing nausea and other gastrointestinal issues after taking their dose.

There's a helpful tip that might reduce these symptoms - you can try splitting your weekly methotrexate dose into three smaller doses taken 12 hours apart during the week. This approach has helped some people better manage their nausea. If you're struggling with persistent nausea, it's important to discuss this with your healthcare provider. They can:
- Adjust your dosing schedule
- Consider changing the way you take the medication (oral vs. injection)
- Monitor your overall health, as regular check-ups are needed while on methotrexate
- Evaluate if you need any changes to your treatment plan

July 2, 2025

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