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A MyPsoriasisTeam Member asked a question 💭
Livermore, CA
November 12, 2025
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MyPsoriasisTeam

Have you noticed flares after starting hormone replacement therapy (HRT)?

Yes, hormonal changes can trigger psoriasis and psoriatic arthritis flares in some people. HRT can affect your symptoms, though experiences vary widely.

Hormone replacement therapy that increases androgens (like testosterone) may worsen psoriasis Show Full Answer

Have you noticed flares after starting hormone replacement therapy (HRT)?

Yes, hormonal changes can trigger psoriasis and psoriatic arthritis flares in some people. HRT can affect your symptoms, though experiences vary widely.

Hormone replacement therapy that increases androgens (like testosterone) may worsen psoriasis and cause flares. A drop in estrogen levels, which some forms of HRT aim to address, has been linked to immune system changes that can trigger flares.

However, responses to hormonal shifts are very individual. Some people experience improvement with certain hormone levels, while others notice worsening symptoms. One MyPsoriasisTeam member shared: "Hormone imbalances cause my psoriasis to flare up."

What you can do:

Talk to both your dermatologist and the doctor prescribing your HRT. They can:
- Evaluate how HRT might be affecting your symptoms
- Adjust your hormone therapy if needed
- Optimize your psoriasis treatment plan

Keep track of when flares occur in relation to starting or changing HRT. This information helps your healthcare team make the best decisions for managing both your hormone needs and your psoriasis.

November 12, 2025

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