How does Vtama work for psoriasis?
Vtama (tapinarof) is a steroid-free topical cream approved for treating plaque psoriasis in adults with mild, moderate, or severe disease. It's applied once daily directly to affected skin anywhere on the body.
How It Works:
Vtama is a new type of medication called an aryl hydrocarbon Show Full Answer
How does Vtama work for psoriasis?
Vtama (tapinarof) is a steroid-free topical cream approved for treating plaque psoriasis in adults with mild, moderate, or severe disease. It's applied once daily directly to affected skin anywhere on the body.
How It Works:
Vtama is a new type of medication called an aryl hydrocarbon receptor (AhR) agonist. It fights psoriasis in two ways:
- In immune cells, it turns off genes related to inflammation
- In skin cells, it helps normalize skin barrier function
Clinical Results:
After three months of use, 35-40% of people in clinical trials were clear or almost clear of psoriasis symptoms.
Key Benefits:
Unlike steroid creams that can only be used short-term, Vtama can be used for unlimited periods of time. This is significant since it's the first new type of topical psoriasis drug approved in the U.S. in 25 years.
Common Side Effects:
Most side effects are mild to moderate and affect the application area:
- Folliculitis (inflamed hair follicles)
- Contact dermatitis
- Itchy skin
- Nasopharyngitis
- Flu-like symptoms
- Headache
April 15
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