Spesolimab (Spevigo) is a biologic that has been explored for palmoplantar pustulosis (PPP), though it's more widely known for treating generalized pustular psoriasis flares. For PPP specifically, biologics are generally considered when other treatments haven't worked.
More commonly used treatments for PPP include:
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Spesolimab (Spevigo) is a biologic that has been explored for palmoplantar pustulosis (PPP), though it's more widely known for treating generalized pustular psoriasis flares. For PPP specifically, biologics are generally considered when other treatments haven't worked.
More commonly used treatments for PPP include:
- Topical corticosteroids (often first-line)
- Calcipotriene cream (Dovonex)
- Phototherapy (UVA, UVB, or PUVA)
- Other biologics for severe cases that don't respond to the above
It's worth bringing up Spevigo specifically with your dermatologist to see if it's an appropriate option for your situation, as treatment plans are very individual. Some MyPsoriasisTeam members managing PPP have also found relief through home care routines — like moisturizing with Hydromol, using aloe vera on affected areas, or soaking in apple cider vinegar — alongside their prescribed treatments. Every little bit can help while you're working with your doctor on the bigger picture! 🙂
August 8
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