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Real members of MyPsoriasisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Did Anyone Here Recently Change Their Biologic Treatment For Psoriasis Or Psoriatic Arthritis?

MyPsoriasisTeam asked a question 💭
San Francisco, CA

Members have shared different experiences with options including Bimzelx, Cosentyx, Skyrizi, and Taltz, etc. What have you tried, and what has the experience been like for you?

October 3, 2025
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Answer Summary

Members shared a wide range of experiences switching biologics for psoriasis and psoriatic arthritis, with popular choices including Tremfya,... Read more

Members shared a wide range of experiences switching biologics for psoriasis and psoriatic arthritis, with popular choices including Tremfya, Skyrizi, Cosentyx, Humira, and Taltz, though results varied greatly from person to person. Several members emphasized that finding the right biologic often takes time and trial, with some experiencing dramatic improvements (like complete clearing or significant pain relief) while others saw limited results, faced side effects like infections or hair loss, or struggled with high costs and insurance coverage changes. A recurring theme was the importance of patience, self-advocacy with doctors and insurance companies, exploring manufacturer assistance programs to reduce costs, and considering complementary approaches like diet changes, gut health support, light therapy, and natural treatments when biologics alone weren't enough.

A MyPsoriasisTeam Member

I started using Tremfya once.  When it was time to reorder Bio Plus wanted me to pay $1500.00.  I switched over to Skyrizi and there was no charge.  Love Skyrizi as it is doing a better job than Tremfya.

Yahoo Mail: Search, Organize, Conquer

October 6, 2025
A MyPsoriasisTeam Member

I have pustular psoriasis, one of the most severe forms, and I completely stopped biological treatments because I noticed that instead of controlling it properly, it caused a lot of changes in my immune system, and the lesions kept coming back every time I missed a treatment. It caused side effects such as a runny nose, constant burning in my eyes, loss of sleep, and worst of all, I never fully recovered. What I did was take a natural alternative. I follow an anti-inflammatory diet, drink natural herbal tea, and also took a natural medicine for leaky gut. If anyone reads this, look into it. An important tip is that if you don't sleep well, your body doesn't renew itself. Right now, I take melatonin and sleep fantastically, and I think I'm better off than I ever was with biological treatments. Take care of your organs if you continue with biological treatments, and get regular checkups. If anyone has any questions, I'm happy to answer them. I hope we can all live in peace with this diseas
e.

October 3, 2025
A MyPsoriasisTeam Member

I have been on Humira for nine months (twice a month). I had to take a break from it due to extensive back surgery. Resuming again and not so sure it has been working. I also was taking Methotrexate. Stopped for surgery and don't want to take again because all of my hair was falling out.

October 3, 2025
A MyPsoriasisTeam Member

I just switched from Rinvoq to consentyx. I’m so happy! All my pain and fatigue is gone. I haven’t felt this good in 6 years. Strongly encourage anyone whose med is not doing a good job to try another. It was not a good month coming off Rinvoq and waiting for cosentyx to kick in. Kinda forgot what full blown disease felt like but it was so worth it. My rheumatologist did give me a steroid shot to get through the worst of it and I am just so happy to have my disease under control now

October 3, 2025
A MyPsoriasisTeam Member

Yep, Abbvie no longer provided my Humira after January 1. Something that apparently affected most folks on Medicare. I used Humira for several years and it was effective in treating my plaque psoriasis. I've been using Cosyntex for four months, and it is not as effective for me as Humira was.

October 30, 2025

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