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Real members of MyPsoriasisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyPsoriasisTeam Member asked a question 💭
Lake Havasu City, AZ
October 21, 2025
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A MyPsoriasisTeam Member

6 weeks on full dose after starter pack, plaques are much worse but I didn’t have any side effects. I’m seeing my derm tomorrow fro discuss other options.

October 29, 2025
MyPsoriasisTeam

Otezla (apremilast) is an FDA-approved oral medication for treating psoriasis at all severity levels. It works by blocking PDE4, an enzyme that triggers inflammation in the body. Over 650,000 people worldwide have used this treatment option.

Clinical studies have shown several benefits
• Reduces plaque size and scaling
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Otezla (apremilast) is an FDA-approved oral medication for treating psoriasis at all severity levels. It works by blocking PDE4, an enzyme that triggers inflammation in the body. Over 650,000 people worldwide have used this treatment option.

Clinical studies have shown several benefits:
• Reduces plaque size and scaling
• Improves skin discoloration
• Helps with nail and scalp psoriasis
• Decreases itching symptoms
• Can improve joint pain and swelling if you have psoriatic arthritis It's important to know about potential side effects, which can include:
• Headache
• Nausea
• Diarrhea
• Cold-like symptoms

The medication has proven particularly helpful for people who find topical treatments insufficient, especially for difficult-to-treat areas like the scalp. Studies showed that people taking Otezla were five times more likely to see improvement in their condition after four months compared to those taking a placebo.

October 21, 2025

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