Has Humira stopped working for your psoriatic arthritis?
Yes, Humira (adalimumab) can lose effectiveness over time for some people with PsA. This happens because your immune system may create antibodies against the medication, recognizing it as a foreign protein rather than a therapeutic treatment.
A MyPsoriasisTeam Show Full Answer
Has Humira stopped working for your psoriatic arthritis?
Yes, Humira (adalimumab) can lose effectiveness over time for some people with PsA. This happens because your immune system may create antibodies against the medication, recognizing it as a foreign protein rather than a therapeutic treatment.
A MyPsoriasisTeam member shared that in 2015, her body stopped responding to Humira after using it successfully for years to manage both her psoriasis and psoriatic arthritis symptoms.
Signs that Humira may be losing effectiveness include:
* Symptoms returning or worsening
* The medication seeming to work but not lasting as long as it used to
* Blood levels of the drug dropping to zero sooner than expected
If you're experiencing this, talk to your doctor. They may consider switching you to a different biologic, adding a disease-modifying antirheumatic drug (DMARD) to your treatment plan, or trying a medication in a new category like a JAK inhibitor.
April 10
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