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A MyPsoriasisTeam Member asked a question 💭
Baltimore, MD

Hi everyone. I was diagnosed with psoriatic arthritis 3 weeks ago. I have been dealing with symptoms since July 2025, and was misdiagnosed by my PCP and the doctors in the ER/Urgent care. My Rheumatologist prescribed me Hadlima, a biosimular to Humaria, and I took my first injection this week. Has anyone had any experience with this medication? How long before you saw a change in your symptoms? Any other advise
My left knee and both of my ankles are swollen, and have caused me the most pain,… read more

April 10
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MyPsoriasisTeam

How long does it typically take to see improvement with Hadlima for psoriatic arthritis symptoms?

Congratulations on getting your diagnosis and starting treatment! It's understandable to be eager for relief, especially with the knee and ankle swelling making it hard to walk.

While everyone responds differently to Show Full Answer

How long does it typically take to see improvement with Hadlima for psoriatic arthritis symptoms?

Congratulations on getting your diagnosis and starting treatment! It's understandable to be eager for relief, especially with the knee and ankle swelling making it hard to walk.

While everyone responds differently to biologics like Hadlima, it's important to know that these medications typically take time to work. Some people may notice improvements within a few weeks, but it can take several months to see the full benefits.

A MyPsoriasisTeam member shared their experience with adalimumab (the medication Hadlima is based on), noting that the combination treatment "saved her skin" when dealing with severe symptoms.

Keep in mind that early treatment is crucial for psoriatic arthritis. Getting ahead of joint inflammation helps prevent serious and potentially irreversible joint damage, which can occur in as little as 6 months if left untreated. Here are some tips while you're waiting for the medication to take effect:

- Stay in close contact with your rheumatologist about your symptoms, especially the knee and ankle swelling
- Ask about over-the-counter options like NSAIDs that might help with pain while the biologic starts working
- Discuss what side effects to watch for and when to reach out if you have concerns
- Consider physical therapy or gentle exercises to help maintain joint mobility
- Track your symptoms so you can report changes (or lack of improvement) to your doctor

If you're not seeing sufficient relief after giving the medication adequate time, or if your symptoms worsen, don't hesitate to reach out to your rheumatologist. Sometimes adjustments to treatment are needed to find what works best for you.

April 10

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