MyPsoriasisTeam

That's a really important concern to raise, and it's great that you're thinking carefully about this. Your dermatologist is right to move away from phototherapy given your skin cancer history, as UV treatment can increase the risk of skin cancers like melanoma.

However, having Hepatitis B antigens is a significant factor Show Full Answer

That's a really important concern to raise, and it's great that you're thinking carefully about this. Your dermatologist is right to move away from phototherapy given your skin cancer history, as UV treatment can increase the risk of skin cancers like melanoma.

However, having Hepatitis B antigens is a significant factor when considering methotrexate. Here's why this matters: Methotrexate can cause cumulative liver toxicity over time, and those with a history of liver disease are generally advised not to take it. Hepatitis B affects the liver, which makes this a serious conversation to have with your dermatologist before starting treatment.

Key points to discuss with your doctor:

- Liver function — Methotrexate is typically avoided in people with liver conditions
- Alternative treatments — Biologics may be worth exploring as an alternative, though they can be more expensive
- Specialist coordination — You may need input from a liver specialist alongside your dermatologist

It's really important to make sure your dermatologist is fully aware of your Hepatitis B status before starting methotrexate. If they already know, ask them directly why they feel it's still safe in your case, and what monitoring they plan to put in place.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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