With a very low risk of any effects otezla has been shown to be a really effective medication for this. It doesn't affect your immune system as far as other immunosuppressants are my specialist says. You do have to have a good gut system though because it can be hard on your digestive system. I found that out firsthand. But I did find out actually in just around a week my plaques were really disappearing. It was incredible. I would have loved to stay on it for that reason but my gut wouldn't cooperate so to speak.

I really like to see the plaques look like they just disappeared then. But it isn't for everyone to use if you have things like IBS etc. It can be harder on your system. Otherwise if you generally have a stronger digestive system I would recommend it. It can be very useful.
Always take medication with food if it allows because it helps absorb best

I know of peptides, yes. I♡the concept of a peptide. I would say yes we do need them for a condition like this just like we need x amount of protein per meal to survive & maintain muscle/bone health. It's basically what is created after consuming foods & or supplements for nutrients. They are proteins but smaller.
😀Check out this animated gif of the formation of a peptide chain below: