Connect with others who understand.

  • Learn from expert-reviewed resources
  • Real advice from people who’ve been there
  • People who understand what you’re going through
Sign Up Log In
Powered By
Real members of MyPsoriasisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
July 7
 · 
Reactions
Can Biologics for Psoriasis Stop Working? Read Article...
MyPsoriasisTeam

It sounds like you've been through quite a journey managing your psoriasis, and it's completely understandable to feel concerned if Xeljanz (tofacitinib) seems to be losing its effectiveness.

There's no single answer for how long a JAK inhibitor will work — it really varies from person to person. Some people stay on the Show Full Answer

It sounds like you've been through quite a journey managing your psoriasis, and it's completely understandable to feel concerned if Xeljanz (tofacitinib) seems to be losing its effectiveness.

There's no single answer for how long a JAK inhibitor will work — it really varies from person to person. Some people stay on the same medication for many years with great results, while others may notice it becoming less effective sooner. Some signs that your medication may be losing strength include:

- Plaques taking longer than usual to clear up
- Psoriasis returning in areas that were previously clear
- Shorter periods of relief between flares

If any of these sound familiar, it's worth bringing up with your doctor as soon as possible. They may consider adjusting your dose or exploring other treatment options.

The good news is there are multiple treatment paths available, so losing response to one medication doesn't mean you're out of options.

July 7

Related Questions

View All