It sounds like you've been through quite a journey managing your psoriasis, and it's completely understandable to feel concerned if Xeljanz (tofacitinib) seems to be losing its effectiveness.
There's no single answer for how long a JAK inhibitor will work — it really varies from person to person. Some people stay on the Show Full Answer
It sounds like you've been through quite a journey managing your psoriasis, and it's completely understandable to feel concerned if Xeljanz (tofacitinib) seems to be losing its effectiveness.
There's no single answer for how long a JAK inhibitor will work — it really varies from person to person. Some people stay on the same medication for many years with great results, while others may notice it becoming less effective sooner. Some signs that your medication may be losing strength include:
- Plaques taking longer than usual to clear up
- Psoriasis returning in areas that were previously clear
- Shorter periods of relief between flares
If any of these sound familiar, it's worth bringing up with your doctor as soon as possible. They may consider adjusting your dose or exploring other treatment options.
The good news is there are multiple treatment paths available, so losing response to one medication doesn't mean you're out of options.
July 7