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List of Treatments for Psoriasis

See what members are saying about treatments for psoriasis and psoriatic arthritis, the side effects to expect, and the drug basics.

All treatment information is medically reviewed · September 22, 2026

Neoral (Cyclosporine)

Overview
Neoral is a prescription medication originally approved by the U.S. Food and Drug Administration (FDA) in 1983. Neoral is approved to treat severe psoriasis in adults who do not respond to other treatments…

Orencia (Abatacept) for Psoriatic Arthritis

Orencia (abatacept) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat people ages 2 and older with active psoriatic arthritis.

Otezla (Apremilast)

Otezla (apremilast) is an oral medication called a phosphodiesterase 4 (PDE4) inhibitor, approved by the U.S. Food and Drug Administration (FDA) for treating psoriasis and psoriatic arthritis in adults and children ages 6 and older.

Otulfi (Ustekinumab-Aauz) for Psoriasis

Otulfi (ustekinumab-aauz) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 and older with moderate to severe plaque psoriasis.

Pyzchiva (Ustekinumab-Ttwe) for Psoriasis

Pyzchiva (ustekinumab-ttwe) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 and older with moderate to severe plaque psoriasis.

Rasuvo (Methotrexate) for Psoriasis

Rasuvo (methotrexate) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to control symptoms of severe, hard-to-treat, disabling psoriasis in adults who have not responded well enough to other treatments.

Remicade (Infliximab) for Psoriasis

Remicade (infliximab) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with chronic severe plaque psoriasis.

Renflexis (Infliximab-Abda) for Psoriasis

Renflexis (infliximab-abda) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with chronic severe plaque psoriasis.

Rinvoq (Upadacitinib) for Psoriatic Arthritis

Rinvoq (upadacitinib) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 2 and older with active psoriatic arthritis.

Selarsdi (Ustekinumab-Aekn) for Psoriasis

Selarsdi (ustekinumab-aekn) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 and older with moderate to severe plaque psoriasis.

Siliq (Brodalumab)

Overview
Siliq is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat moderate to severe psoriasis in adults. Siliq may be prescribed in cases where systemic therapy and phototherapy are…

Simlandi (Adalimumab-Ryvk) for Psoriasis and Psoriatic Arthritis

Simlandi (adalimumab-ryvk) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis and active psoriatic arthritis.

Simponi (Golimumab) for Psoriatic Arthritis

Simponi (golimumab) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with active psoriatic arthritis.

Simponi Aria (Golimumab) for Psoriatic Arthritis

Simponi Aria (golimumab) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat active psoriatic arthritis in people 2 years of age and older.

Skyrizi (Risankizumab-Rzaa) for Psoriasis

Skyrizi (risankizumab-rzaa) is a biologic medication approved by the U.S. Food and Drug Administration (FDA) for adults with moderate to severe psoriasis who need systemic (bodywide) therapy or phototherapy.

Soriatane (Acitretin) for Psoriasis

Soriatane (acitretin) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with severe psoriasis.

Sorilux (Calcipotriene) for Psoriasis

Sorilux (calcipotriene) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat plaque psoriasis of the scalp and body in adults and children ages 4 and older.

Sotyktu (Deucravacitinib) for Psoriasis

Sotyktu (deucravacitinib) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe plaque psoriasis.

Spevigo (Spesolimab-Sbzo) for Generalized Pustular Psoriasis

Spevigo (spesolimab-sbzo) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat generalized pustular psoriasis (GPP) in adults and children ages 12 and older who weigh at least 40 kilograms.

Starjemza (Ustekinumab-Hmny) for Psoriasis

Starjemza (ustekinumab-hmny) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 and older with moderate to severe plaque psoriasis.

Stelara (Ustekinumab) for Psoriasis

Stelara (ustekinumab) is a medication approved by the U.S. Food and Drug Administration (FDA) for treating moderate to severe plaque psoriasis in adults and children 6 years and older who may benefit from injections, pills, or light therapy.

Steqeyma (Ustekinumab-Stba) for Psoriasis

Steqeyma (ustekinumab-stba) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 years and older with moderate to severe plaque psoriasis.

Taclonex (Calcipotriene/Betamethasone Dipropionate) for Plaque Psoriasis

Taclonex (calcipotriene/betamethasone dipropionate) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat plaque psoriasis in people ages 12 years and older.

Taltz (Ixekizumab) for Psoriasis

Taltz (ixekizumab) is a biologic medication approved by the U.S. Food and Drug Administration (FDA) for treating moderate to severe plaque psoriasis in adults and children 6 years and older who may benefit from systemic therapy or light therapy.

Tazorac (Tazarotene) for Psoriasis

Tazorac (tazarotene) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat people with plaque psoriasis.

Tremfya (Guselkumab) for Psoriasis

Tremfya (guselkumab) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating moderate to severe plaque psoriasis in adults who may benefit from injections, pills, or light therapy.

Trexall (Methotrexate) for Psoriasis

Trexall (methotrexate) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with severe psoriasis.

Vectical (Calcitriol)

Overview
Vectical is a prescription medication approved by the U.S. Food and Drug Administration (FDA) in 2009. Vectical is used to treat mild to moderate plaque psoriasis in adults 18 years and older. Vectical is also…

Vtama (Tapinarof Cream) for Psoriasis

Vtama (tapinarof cream) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with plaque psoriasis.

Wezlana (Ustekinumab-Auub) for Psoriasis

Wezlana (ustekinumab-auub) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat moderate to severe plaque psoriasis in adults and children ages 6 years and older.

Wynzora (Calcipotriene and Betamethasone Dipropionate) for Psoriasis

Wynzora (calcipotriene and betamethasone dipropionate) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat plaque psoriasis in adults ages 18 and older.

Xeljanz (Tofacitinib) for Psoriatic Arthritis

Xeljanz (tofacitinib) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) for treating adults and children ages 2 years and older with active psoriatic arthritis.

Yesintek (Ustekinumab-Kfce) for Psoriasis

Yesintek (ustekinumab-kfce) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults and children ages 6 years and older with moderate to severe plaque psoriasis.

Yuflyma (Adalimumab-Aaty) for Psoriasis and Psoriatic Arthritis

Yuflyma (adalimumab-aaty) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis or active psoriatic arthritis.

Yusimry (Adalimumab-Aqvh) for Psoriasis and Psoriatic Arthritis

Yusimry (adalimumab-aqvh) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe chronic plaque psoriasis and active psoriatic arthritis.

Zoryve (Roflumilast) for Plaque Psoriasis

Zoryve (roflumilast) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat plaque psoriasis in certain adults and children. It comes as a cream and a topical foam.

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